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KMID : 0914820060060010031
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Journal of the Korean Gastric Cancer Association
2006 Volume.6 No. 1 p.31 ~ p.35
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Primary Adenosquamous Carcinoma of the Stomach
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Cho Yong-Gwon
Ahn Ji-Young
Hong Sung-Kwon
Choi Min-Gew
Noh Jae-Hyung
Sohn Tae-Sung
Kim Sung
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Abstract
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Purpose: A primary adenosquamous carcinoma of the stomach is relatively rare, accounting for only about 0.5% of all gastric cancers. However, its histopathologic characteristics are still unclear, and the most appropriate form of therapy has not been established yet.
Materials and Methods: We retrospectively reviewed the clinicopathologic features of 8 patients with pathologically confirmed primary adenosquamous carcinomas out of 8,268 patients who underwent gastric cancer surgery at Samsung Medical Center between September 1994 and December 2004.
Results: The median age of the 8 patients was 49 (41∼69) years, and the male：female ratio was 5：3. In 3 patients, the tumor was located at the mid body of the stomach, and in 5 patients, at the lower body or antrum. The tumor sizes were 2.5∼8 cm. Seven patients showed metastases to the regional lymph nodes. The UICC stage distribution were: 5 stage II, 2 stage III, and 1 stage IV. In the stage IV patient, a palliative gastrojejunostomy was performed, and he died 5 months after surgery. Of the 7 patients who underwent a radical gastrectomy and adjuvant chemotheratpy, the median survival was 34 (12∼66) months, 2 patients died of cancer recurrence, and 4 patients are being followed up without evidence of recurrence.
Conclusion: As for an adenocarcinoma of the stomach, a radical gastrectomy including regional lymph node dissection and postoperative adjuvant therapy should be performed for appropriate treatment of an adenosquamous carcinoma of the stomach. (J Korean Gastric Cancer Assoc 2006;6:31-35)
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KEYWORD
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Gastric cancer, Adenosquamous carcinoma, Gastrectomy, Prognosis
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